Dirk E. Smith,Ian Foltz,Chadwick T. King,Ai Ching Lim,Rutilio Clark,Michael R. Comeau,Randal R. Ketchem,Donghui Shi,Xiaoshan Min,Zhulun Wang
申请号:
US15178652
公开号:
US09982054B2
申请日:
2016.06.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and deriviatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.