SMITH, DIRK E.,FOLTZ, IAN,KING, CHADWICK T.,LIM, AI CHING,CLARK, RUTILIO,COMEAU, MICHAEL R.,KETCHEM, RANDAL R.,SHI, DONGHUI,MIN, XIAOSHAN,WANG, ZHULUN
申请号:
SG11201407564T
公开号:
SG11201407564TA
申请日:
2013.05.17
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and deriviatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.