SMITH DIRK E,FOLTZ IAN,KING CHADWICK T,LIM AI CHING,CLARK RUTILIO,COMEAU MICHAEL R,KETCHEM RANDAL R,SHI DONGHUI,MIN XIAOSHAN,WANG ZHULUN
申请号:
IN9219/DELNP/2014
公开号:
IN2014DN09219A
申请日:
2014.11.03
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and derivatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.