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STABLE, LOW VISCOSITY ANTIBODY FORMULATION
专利权人:
LLC;MEDIMMUNE
发明人:
BEE, JARED,SANTACROCE, PAUL,DU, JIALI,DIMITROVA, MARIANA
申请号:
SG11201502659Y
公开号:
SG11201502659YA
申请日:
2013.10.23
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23° C. Also provided are methods of making and methods of using such antibody formulations.
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中国工程科技知识中心
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