Jared Bee,Paul Santacroce,Jiali Du,Mariana Dimitrova,BEE, Jared,SANTACROCE, Paul,DU, Jiali,DIMITROCA, Mariana
申请号：
US14437585
公开号：
US20150239970A1
申请日:
2013.10.23
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23° C. Also provided are methods of making and methods of using such antibody formulations.
