Pamela Mary Holland,Jonathan David Graves,Jennifer Joy Kordich,Julia Catherine Piasecki,Ian Nevin Foltz
申请号：
US16176343
公开号：
US20190284290A1
申请日:
2018.10.31
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention includes apoptotic compositions and methods for inducing apoptosis of cancer cells independent of NK cells. An apoptotic composition comprises a cooperative combination of antibodies that specifically bind to human DR5, or a cooperative combination of an anti-DR5 antibody and TRAIL. Administration of therapeutically effective amounts of an apoptotic composition induces apoptosis of apoptosis sensitive cancer cells.
