Thomas E. Rawson;Richard Pastor;Emily Hanan;Steven R. Magnuson;Bing-Yan Zhu;Paul A. Gibbons;Joseph P. Lyssikatos;Jeffrey Blaney;Aihe Zhou
发明人:
Jeffrey Blaney,Paul A. Gibbons,Emily Hanan,Joseph P. Lyssikatos,Steven R. Magnuson,Richard Pastor,Thomas E. Rawson,Aihe Zhou,Bing-Yan Zhu
申请号：
US13099179
公开号：
US08637526B2
申请日:
2011.05.02
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides JAK kinase inhibitors of Formula Ia, enantiomers, diasteriomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and Z are defined herein, a pharmaceutical composition that includes a compound of Formula Ia and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a JAK kinase activity in a patient.
