KRASUTSKY, ALEXEI PAVLOVYCH,SNYDER, NANCY JUNE,WALLACE, OWEN BRENDAN,XU, YANPING,YORK, JEREMY SCHULENBURG
申请号:
CA2649111
公开号:
CA2649111C
申请日:
2007.04.24
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention discloses novel compounds of Formula I: having 11.beta. -HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11.beta.-HSD type 1 activity.