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Pieridinyl substituted pyrrolidinones as inhibitors of 11-Beta-hydroxysteroid dehydrogenase 1
专利权人:
Eli Lilly and Company
发明人:
Wallace, Owen Brendan,York, Jeremy Schulenburg,Xu, Yanping
申请号:
AU2007244742
公开号:
AU2007244742B2
申请日:
2007.04.27
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
ABSTRACT The present invention discloses novel compounds of Formula I: ( I ) having 11-Beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11-Beta-HSD type 1 activity. X-17433 PCT -1-
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