Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

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专利权人:

Renhua Li

发明人:

Renhua Li,Owen Brendan Wallace,Yanping Xu

申请号：

US12297910

公开号：

US08148534B2

申请日:

2007.04.25

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention discloses novel compounds of Formula I: (I) possessing 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, cognitive disorders, and other conditions associated with 11β-HSD type 1 activity.

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