Julie Kay Bush,Marvin Martin Hansen,Renhua Li,Thomas Edward Mabry,Nancy June Snyder,Owen Brendan Wallace,Yanping Xu
申请号:
US12297873
公开号:
US08153807B2
申请日:
2007.04.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention discloses novel compounds of Formula I: (I) having 11-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11-HSD type 1 activity.