Thorsten Oost;Liliane Unger;Charles W. Hutchins;Alfred Hahn;Wilfried Hornberger;Herve Genesle;Wilfried Lubisch;Astrid Netz
发明人:
Herve Genesle,Thorsten Oost,Charles W. Hutchins,Liliane Unger,Wilfried Hornberger,Wilfried Lubisch,Astrid Netz,Wolfgang Wernet
申请号：
US12529542
公开号：
US08486931B2
申请日:
2008.02.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to compounds of the general formula (I)in which A, B, R1, R2 and Het have the meaning given in claim 1； Y is a bivalent group of the formulain which D is C1-C3-alkylene, where D may have a substituent R5； R3 is hydrogen, C1-C8-alkyl or together with R4 is C1-C3-alkylene which may have a radical R5a, or together with R5 is C1-C3-alkylene, and R4 is hydrogen, C1-C8-alkyl or together with R3 is C1-C3-alkylene which may have a radical R5a, or together with R5 is C1-C3-alkylene, where R5 together with R5a, where present, are a bond or C1-C3-alkylene； and where one of the following conditions is satisfied: R3 together with R4 is C1-C3-alkylene which may have a radical R5a； or R3 together with R5 is C1-C3-alkylene； or R4 together with R5 is C1-C3-alkylene where the radical A is different from phenyl when the radical B is phenyl or naphthyl；and medicaments which comprise such compounds and the use thereof for the prophylaxis and/or treatment of vasopressin-dependent and/or oxytocin-dependent diseases.
