Disclosed is a method for supporting a diagnosis of a risk of colorectal cancer recurrence. The method comprises the steps of: performing a first measurement to measure levels of expression of a plurality of genes selected from a first gene group present in a region from 18q21 to 18q23 on a long arm of chromosome 18 in a biological sample collected from a patient with colorectal cancer, a second measurement to measure levels of expression of a plurality of genes selected from a second gene group present in a region from 20q11 to 20q13 on a long arm of chromosome 20, and a third measurement to measure levels of expression of a plurality of genes selected from a third gene group consisting of ANGPTL2, AXL, C1R, C1S, CALHM2, CTSK, DCN, EMP3, GREM1, ITGAV, KLHL5, MMP2, RAB34, SELM, SRGAP2P1, and VIM； and determining the risk of colorectal cancer recurrence of the patient based on results of the first measurement, second measurement and third measurement.
