JOLLY, DOUGLAS J.,LIN, AMY H.,HOFACRE, ANDREW,HOGAN, DANIEL J.,OSTERTAG, DEREK G.
申请号:
CA2996797
公开号:
CA2996797A1
申请日:
2016.09.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
This disclosure provides modified recombinant retroviruses comprisings containing a 2A-peptide or peptide-like coding sequence operably linked to a heterologous polynucleotide. The disclosure further relates to cells and vector expressing or comprising such vectors and methods of using such modified vectors in the treatment of disease and disorders.