JOLLY, Douglas,LIN, Amy, H,HOFACRE, Andrew,HOGAN, Daniel J.,OSTERTAG, Derek G.
申请号:
PH12018500477
公开号:
PH12018500477A1
申请日:
2018.03.05
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
This disclosure provides modified recombinant retroviruses comprisings containing a 2A-peptide or peptide-like coding sequence operably linked to a heterologous polynucleotide. The disclosure further relates to cells and vector expressing or comprising such vectors and methods of using such modified vectors in the treatment of disease and disorders.