Douglas J. Jolly,Amy H. Lin,Andrew Hofacre,Daniel J. Hogan,Derek G. Ostertag
申请号:
US15757292
公开号:
US20180251786A1
申请日:
2016.09.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This disclosure provides modified recombinant retroviruses comprisings containing a 2A-peptide or peptide-like coding sequence operably linked to a heterologous polynucleotide. The disclosure further relates to cells and vector expressing or comprising such vectors and methods of using such modified vectors in the treatment of disease and disorders.