Chromene derivatives substituted by alkoxide as inhibitors of the TCR-Nck interaction

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专利权人:

Artax Biopharma Inc.

发明人:

Gagete Mateos, Andres,Castro Palomino, Julio,Marti Clauzel, Luc,Tormo Carulla, Damia

申请号：

AU2014335859

公开号：

AU2014335859A1

申请日:

2014.10.20

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention relates to a group of compounds of formula (I) containing chromene nucleus : (I) and that present the capacity to inhibit the proliferation of lymphocytes mediated by the Nck interaction with TCR, so that the present invention also relates to the use of these compounds for the treatment of diseases or conditions where said interaction triggers a complication such as transplant rejection reactions, immune or autoimmune diseases, inflammatory diseases or proliferative diseases.

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