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Alkoxide substituted chromene derivatives as inhibitors of the TCR-Nck interaction
专利权人:
Artax Biopharma Inc.
发明人:
GAGETE MATEOS, Andrés,CASTRO PALOMINO, Julio,MARTI CLAUZEL, Luc,TORMO CARULLA, Damiá
申请号:
ES14809703
公开号:
ES2719115T3
申请日:
2014.10.20
申请国别(地区):
ES
年份:
2019
代理人:
摘要:
The present invention relates to a group of compounds of formula (I) containing a chromene nucleus: and that present the capacity to inhibit the proliferation of lymphocytes mediated by the Nck interaction with TCR, so that the present invention also relates to the use of these compounds for the treatment of diseases or conditions where said interaction triggers a complication such as transplant rejection reactions, immune or autoimmune diseases, inflammatory diseases or proliferative diseases.
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