CAO ZHU ALEXANDER,SACI ABDEL,VANASSE K GARY J,GROWNEY JOSEPH DANIEL
申请号:
IN201617001982
公开号:
IN201617001982A
申请日:
2016.01.19
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates to a Pim kinase inhibitor compound that can be used alone or in a pharmaceutical combination. One such combination comprises (a) a JAK inhibitor compound (b) a Pim kinase inhibitor compound and optionally at least one pharmaceutically acceptable carrier for simultaneous separate or sequential use in particular for the treatment of a myeloid neoplasm or leukemia; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of myeloid neoplasm or leukemia; a commercial package or product comprising such a combination as a combined preparation for simultaneous separate or sequential use; and to a method of treatment of a mammal especially a human.