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Pim kinase inhibitor combinations
专利权人:
Novartis AG
发明人:
CAO, Zhu Alexander,SACI, Abdel,VANASSE, K. Gary J.,GROWNEY, Joseph Daniel
申请号:
AU2017210520
公开号:
AU2017210520A1
申请日:
2017.08.01
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2017210520A120170817.pdf#####1: dar Intrwovn NRPortbl DCC DAR 15366616_l.docx-27 07/2017 ABSTRACT The present invention relates to a Pim kinase inhibitor compound that can be used alone or in a pharmaceutical combination. One such combination comprises (a) a JAK inhibitor compound, (b) a Pim kinase inhibitor compound, and optionally, at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the treatment of a myeloid neoplasm or leukemia; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of myeloid neoplasm or leukemia; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a mammal, especially a human.
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