Cao, Zhu Alexander,Saci, Abdel,Vanasse, K. Gary J.,Growney, Joseph Daniel
申请号:
AU2014304126
公开号:
AU2014304126A1
申请日:
2014.08.07
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention relates to a Pim kinase inhibitor compound that can be used alone or in a pharmaceutical combination. One such combination comprises (a) a JAK inhibitor compound, (b) a Pim kinase inhibitor compound, and optionally, at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the treatment of a myeloid neoplasm or leukemia; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of myeloid neoplasm or leukemia; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a mammal, especially a human.