Shivali Ashwin Gulab;Gary Brian Evans;Keith Clinch;Peter Charles Tyler;Peter Michael Kelly;Anthony David Woolhouse;Richard Hubert Furneaux;Vern L. Schramm
发明人:
Keith Clinch,Gary Brian Evans,Richard Hubert Furneaux,Shivali Ashwin Gulab,Peter Michael Kelly,Vern L. Schramm,Peter Charles Tyler,Anthony David Woolhouse
申请号：
US12310708
公开号：
US08853224B2
申请日:
2007.09.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
