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Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases
专利权人:
INDUSTRIAL RESEARCH LIMITED;Albert Einstein College of Medicine of Yeshiva University
发明人:
Evans, Gary Brian,Woolhouse, Anthony David,Kelly, Peter Michael,Clinch, Keith,Furneaux, Richard Hubert,Tyler, Peter Charles,Schramm, Vern L.,Gulab, Shivali Ashwin
申请号:
AU2007293774
公开号:
AU2007293774C1
申请日:
2007.09.07
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
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