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Fast dissolving solid dosage formulation comprising functionalized calcium carbonate and process for the preparation thereof
专利权人:
Omya International AG
发明人:
GANE, Patrick A.C.,ALLES, Rainer,Huwyler, Jörg,Stirnimann, Tanja,Puchkov, Maxim,Schölkopf, Joachim,Gerard, Daniel E.
申请号:
DK12188344
公开号:
DK2719373T3
申请日:
2012.10.12
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
An orally fast disintegrating dosage forms comprising functionalized natural or synthetic calcium carbonate, at least one active ingredient and at least one disintegrant, wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source, and wherein the tablet dissolves in less than 20 seconds when introduced into an aqueous environment.
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