"A PROCESS FOR MAKING SOLID DOSAGE FORM COMPRISING DOXYCYCLINE CALCIUM COMPLEX "

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专利权人:

发明人:

TINA M DEVRIES,LYNN GOLD

申请号：

IN6130/DELNP/2005

公开号：

IN250480B

申请日:

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

The present invention relates to a process for making the solid dosage form comprising a doxycycline calcium complex, wherein the complex consists of doxycycline and calcium, the process comprising the step of:(i) providing an aqueous solution of doxycycline or a physiologically acceptable saltthereof(ii) admixing a metal calcium salt with said aqueous solution,(iii) admixing a base to increase the pH of said aqueous solution, thereby forming asuspension of doxycycline metal calcium complex and(iv) drying said suspension, thereby forming a dry granulation of doxycycline calciumcomplex.

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