LEE EUNKYUNG,이은경,KIM TAE SEONG,김태성,SEO, SEONG KYUNG,서성경
申请号：
KR1020117028123
公开号：
KR1020120056800A
申请日:
2009.09.08
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A composition for reducing glucagon signal transduction activity is provided to suppress the activation of glucagon receptor.CONSTITUTION: An isolated antibody, antigen-binding site, or derivative thereof contains heavy chain CDRs which are successively contained in an amino acid sequence of sequence number 2, 4, 6, 8, 10, 12, 14, or 16 a light chain CDRs which are successively contained in an amino acid sequence of sequence number 18, 20, 22, 24, 26, 28, or 30 or combination thereof. A method of treating, preventing, or suppressing type 2 diabetes, dyslipidemia, or diseases thereof comprises a step of administering a pharmaceutical composition containing the isolated antibody, antigen-binding site or derivative, or antibody.COPYRIGHT KIPO 2012글루카곤 수용체에 대한 항체를 사용하여 글루카곤 신호전달의 활성도를 감소시키기 위한 방법 및 조성물이 공개되었다.
