LI, LIN,SHIVELY, JOHN ERNEST,SWIDERSKI, PIOTR MAREK,HERRMANN, ANDREAS,YU, HUA
申请号:
PH12016500395
公开号:
PH12016500395A1
申请日:
2016.02.29
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
Provided herein are cell penetrating conjugates. The conjugates include a non-cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone, wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of the non-cell penetrating protein. Also provided are compositions and kits comprising the cojugates.