Andreas Herrmann,Hua Yu,Piotr Marek Swiderski,John Ernest Shively,Lin Li
申请号：
US15056777
公开号：
US20160317671A1
申请日:
2016.02.29
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided herein are cell penetrating conjugates. The conjugates include a non-cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone, wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of the non-cell penetrating protein. Also provided are compositions and kits comprising the cojugates.
