LI LIN,SHIVELY JOHN ERNEST,SWIDERSKI PIOTR MAREK,HERRMANN ANDREAS,YU HUA
申请号:
IN201617009848
公开号:
IN201617009848A
申请日:
2016.03.21
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Provided herein are cell penetrating conjugates. The conjugates include a non cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of the non cell penetrating protein. Also provided are compositions and kits comprising the cojugates.