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Aurora and FLT3 kinases modulators
专利权人:
发明人:
John Charles Reader
申请号:
US14376729
公开号:
US09133180B2
申请日:
2013.02.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides a compound having the formula (1):and salts thereof wherein:R1 is hydrogen or C1-2 alkyl andR2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen.Also provided are pharmaceutical compositions containing the compounds and their use in medicine, and in particular in the treatment of cancer.
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