Giuseppe COLOMBO,Roberta ARTICO,Paolo MASCAGNI,Maria Valmen MONZANI,Silvia PUCCIANTI
申请号：
US15770443
公开号：
US20180311160A1
申请日:
2016.10.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Physically and chemically stable oral liquid formulations of Givinostat (Diethyl-[6-(4-hydroxycarbamoyl-phenylcarbamoyloxymethyl)-naphthalen-2-yl-methyl]-ammonium chloride) are disclosed, together with methods for the preparation thereof. Such oral formulations are in the form of aqueous suspensions and contain Givinostat and/or pharmaceutically acceptable salts and/or derivatives thereof, at least a wetting agent and/or at least a density-imparting agent. Such formulations are suitable for oral administration for systemic therapeutic action.
