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SUSPENSIONS ORALES DE GIVINOSTAT PHYSIQUEMENT ET CHIMIQUEMENT STABLES
专利权人:
ITALFARMACO SPA
发明人:
COLOMBO, GIUSEPPE,ARTICO, ROBERTA,MASCAGNI, PAOLO,MONZANI, MARIA VALMEN,PUCCIANTI, SILVIA
申请号:
CA3002755
公开号:
CA3002755A1
申请日:
2016.10.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Physically and chemically stable oral liquid formulations of Givinostat (Diethyl- [6-(4- hydroxycarbamoyl-phenylcarbamoyloxymethyl)-naphthalen-2-yl-methyl]-ammonium chloride) are disclosed, together with methods for the preparation thereof. Such oral formulations are in the form of aqueous suspensions and contain Givinostat and/or pharmaceutically acceptable salts and/or derivatives thereof, at least a wetting agent and/or at least a density-imparting agent. Such formulations are suitable for oral administration for systemic therapeutic action.
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