Colombo, Giuseppe,Artico, Roberta,Mascagni, Paolo,Monzani, Maria Valmen,Puccianti, Silvia
申请号:
AU2016349169
公开号:
AU2016349169A1
申请日:
2016.10.28
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Physically and chemically stable oral liquid formulations of Givinostat (Diethyl- [6-(4- hydroxycarbamoyl-phenylcarbamoyloxymethyl)-naphthalen-2-yl-methyl]-ammonium chloride) are disclosed, together with methods for the preparation thereof. Such oral formulations are in the form of aqueous suspensions and contain Givinostat and/or pharmaceutically acceptable salts and/or derivatives thereof, at least a wetting agent and/or at least a density-imparting agent. Such formulations are suitable for oral administration for systemic therapeutic action.