COLOMBO, Giuseppe,ARTICO, Roberta,MASCAGNI, Paolo,MONZANI, Maria Valmen,PUCCIANTI, Silvia
申请号:
ITUB20155193
公开号:
ITUB20155193A1
申请日:
2015.11.03
申请国别(地区):
IT
年份:
2017
代理人:
摘要:
Physically and chemically stable oral liquid formulations of Givinostat (Diethyl-[6-(4-hydroxycarbamoyl-phenylcarbamoyloxymethyl)-naphthalen-2-yl-methyl]-ammonium chloride) are disclosed, together with methods for the preparation thereof. Such oral formulations are in the form of aqueous suspensions and contain Givinostat and/or pharmaceutically acceptable salts and/or derivatives thereof, at least a wetting agent and/or at least a density-imparting agent. Such formulations are suitable for oral administration for systemic therapeutic action.