COMBINAISON DE COMPOSÉS INHIBITEURS DE LA PHOSPHOINOSITIDE 3-KINASE ET D'AGENTS CHIMIOTHÉRAPEUTIQUES POUR LE TRAITEMENT DE TUMEURS MALIGNES HÉMATOPOÏÉTIQUES

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专利权人:

Genentech; Inc.

发明人:

申请号：

EP10708866.8

公开号：

EP2405916B1

申请日:

2010.03.11

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Combinations of PI3K inhibitor compounds having Formula I and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hematopoietic malignancies. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

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