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Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
专利权人:
Allen J. Ebens, Jr.;Lori Friedman;Allen J. Ebens; Jr.
发明人:
Allen J. Ebens, Jr.,Lori Friedman
申请号:
US12721645
公开号:
US08536161B2
申请日:
2010.03.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Combinations of PI3K inhibitor compounds having Formula I and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hematopoietic malignancies. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
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