The University of Tokyo;Chugai Seiyaku Kabushiki Kaisha
发明人:
申请号：
EP14841672.0
公开号：
EP3042955B1
申请日:
2014.09.04
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Disclosed are a novel method of detecting cancer, a method of screening inhibitors and anticancer agents that target cancer-related molecules, RHOA polypeptide having mutation and a polynucleotide encoding the polypeptide as a therapeutic agent for cancer, and a method of detecting cancer using the polypeptide or polynucleotide. Also disclosed are a vector and a host cell comprising the polynucleotide, a method of screening therapeutic agents for cancer comprising the polypeptide and/or the polynucleotide, and a therapeutic agent for cancer comprising siRNA having a silencing effect on RHOA mutant.
