USE OF RHOA IN CANCER DIAGNOSIS AND INHIBITOR SCREENING

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专利权人:

The University of Tokyo

发明人:

ABURATANI, Hiroyuki,ISHIKAWA, Shumpei,KAKIUCHI, Miwako,NISHIZAWA, Takashi

申请号：

EP14841672

公开号：

EP3042955A4

申请日:

2014.09.04

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Disclosed are a novel method of detecting cancer, a method of screening inhibitors and anticancer agents that target cancer-related molecules, RHOA polypeptide having mutation and a polynucleotide encoding the polypeptide as a therapeutic agent for cancer, and a method of detecting cancer using the polypeptide or polynucleotide. Also disclosed are a vector and a host cell comprising the polynucleotide, a method of screening therapeutic agents for cancer comprising the polypeptide and/or the polynucleotide, and a therapeutic agent for cancer comprising siRNA having a silencing effect on RHOA mutant.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/