BETHEL, Richard,ENEROTH, Anders,KLASSON, Bj”rn,™BERG, Fredrik
申请号：
PH12017500184
公开号：
PH12017500184B1
申请日:
2017.01.31
申请国别(地区):
PH
年份:
2017
代理人:
摘要：
The invention provides compounds of formula (I), wherein: R1 is OR11, or NR5R5'； R2 is H or F； R5 is H, C1-C6alkyl, OH, C(=O)R6, O(C=O)R6 or O(C=O)OR6； R5' is H or C1-C6alkyl； R6 is C1-C6alkyl or C3-C7cycloalkyl； R13 is H, phenyl, pyridyl, benzyl, indolyl or naphthyl wherein the phenyl, pyridyl, benzyl, indolyl and naphthyl is optionally substituted with 1, 2, 3 R22； and the other variables are as defined in the claims, which are of use in the treatment of cancer, and related aspects.
