BETHEL, RICHARD,ENEROTH, ANDERS,KLASSON, BJORN,OBERG, FREDRIK
申请号：
CA2956251
公开号：
CA2956251A1
申请日:
2015.08.24
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention provides compounds of formula (I), wherein: R1 is OR11, or NR5R5'； R2 is H or F； R5 is H, C1-C6alkyl, OH, C(=O)R6, O(C=O)R6 or O(C=O)OR6； R5´ is H or C1-C6alkyl； R6 is C1-C6alkyl or C3-C7cycloalkyl； R13 is H, phenyl, pyridyl, benzyl, indolyl or naphthyl wherein the phenyl, pyridyl, benzyl, indolyl and naphthyl is optionally substituted with 1, 2 or 3 R22； and the other variables are as defined in the claims, which are of use in the treatment of cancer, and related aspects.
