Richard BETHELL,Anders ENEROTH,Bjorn KLASSON,Fredrik OBERG
申请号：
US16459165
公开号：
US20190389890A1
申请日:
2019.07.01
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention provides compounds of the formula:R1 is OR11, or NR5R5′；；R2 is H or F；R5 is H, C1-C6alkyl, OH, C(═；O)R6, O(C═；O)R6 or O(C═；O)OR6；R5′； is H or C1-C6alkyl；R6 is C1-C6alkyl or C3-C7cycloalkyl；R13 is H, phenyl, pyridyl, benzyl, indolyl or naphthyl wherein the phenyl, pyridyl, benzyl, indolyl and naphthyl is optionally substituted with 1, 2 or 3 R22；and the other variables are as defined in the claims,which are of use in the treatment of cancer, and related aspects.
