"compound of formula I, pharmaceutical composition, method for inhibiting abnormal cell growth or treating a hyperproliferative disorder in a mammal and method for treating an inflammatory disease in a mammal"
STEPHEN PRICE,JOANNE FRANCES MARY HEWITT,MARK. E. ZAK,ROBERT HEALD,WENDY LEE
申请号:
BRPI0819529
公开号:
BRPI0819529A2
申请日:
2008.12.18
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention relates to imidazopyridines of formula 1 with anti-cancer and/or anti-inflammatory activity and more specifically to imidazopyridines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.