作為TTX-S阻斷劑之雙芳氧基衍生物农业专利-农业学术服务平台

发明人:: KAWAMURA, KIYOSHI,川村清,YAMAGISHI, TATSUYA,山岸竜也,SHISHIDO, YUJI,宍戸佑二,宍戸祐二,MORITA, MIKIO,森田干雄,森田幹雄,YAMAGUCHI, RYUICHI,山口龙一,山口龍一,OHMI, MASASHI,大见仁,大見仁

摘要：: The present invention relates to biaryloxy derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channel is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.本發明係有關雙芳氧基衍生物，其具有電位閘控鈉通道例如TTX-S通道的阻斷活性，並且可用於治療或預防與電位閘控鈉通道相關之病症和疾病。本發明亦係有關包含該等化合物之醫藥組合物和該等化合物及組合物於預防或治療與電位閘控鈉通道相關之疾病中之用途。