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PHARMACEUTICAL SOLID PREPARATION AND METHOD OF PRODUCTION
专利权人:
OTSUKA PHARMACEUTICAL CO.; LTD.
发明人:
SHINSUKE NAKAGAWA,KAI SUZUKI,TADASHI MUKAI
申请号:
BRPI0813100
公开号:
BRPI0813100A2
申请日:
2008.06.20
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The subject invention provides a novel pharmaceutical solid preparation that has superior disintegration properties and excellent solubility, leading to sufficient absorbability of active ingredients through the gastrointestinal tract. The pharmaceutical solid preparation of the present invention comprises: (a) 7-chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzoazepine and/or salt thereof; (b) hydroxypropylcellulose containing a hydroxypropoxyl group in an amount of 50 wt. % or greater; and (c) at least one member selected from the group consisting of carmellose, sodium carboxy methyl starch, crospovidone, and low substituted hydroxypropylcellulose with an average particle diameter of 30 to 70 μm, and a 90% cumulative particle diameter of 100 to 200 μm.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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