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Stabilized amorphous forms of imatinib mesylate
专利权人:
发明人:
申请号:
EP10178116.9
公开号:
EP2305263B1
申请日:
2007.06.07
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention relates to the stabilized amorphous form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-(pyridin-3-yl)-pyrimidin-2-ylamino)-phenyl]-benzamide, pharmaceutical compositions such as capsules or tablets containing this form, the use of such form in diagnostic methods or, preferably, for the therapeutic treatment of warm-blooded animals, especially humans, and the use of formulation principles stabilizing the amorphous form of Imatinib mesylate as an intermediate for the preparation of pharmaceutical compositions.
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