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Stabilized Amorphous Forms of Imatinib Mesylate
专利权人:
Elisabete Goncalves
发明人:
Elisabete Goncalves,Oskar Kalb,Michael Mutz,Wolfgang Wirth,Jay Parthiban Lakshman
申请号:
US13625345
公开号:
US20130022672A1
申请日:
2012.09.24
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to the stabilized amorphous form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-(pyridin-3-yl)-pyrimidin-2-ylamino)-phenyl]-benzamide, pharmaceutical compositions such as capsules or tablets containing this form, the use of such form in diagnostic methods or, preferably, for the therapeutic treatment of warm-blooded animals, especially humans, and the use of formulation principles stabilizing the amorphous form of lmatinib mesylate as an intermediate for the preparation of pharmaceutical compositions.
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