Goncalves, Elisabete,Lakshman, Jay Parthiban,Wirth, Wolfgang,Kalb, Oskar,Mutz, Michael
申请号：
AU2012201613
公开号：
AU2012201613B2
申请日:
2012.03.19
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2012201613B220141204.pdf#####Abstract The invention relates to the stabilized amorphous form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin- 1-ylmethyl)-N-[4-methyl-3-(4-(pyridin-3-yl)-pyrimidin2-ylamino)-phenyl]-benzamide, pharmaceutical compositions such as capsules or tablets containing this form, the use of such form in diagnostic methods or, preferably, for the therapeutic treatment of warm-blooded animals, especially humans, and the use of formulation principles stabilizing the amorphous form of Imatinib mesylate as an intermediate for the preparation of pharmaceutical compositions.
