LEE, HAN KOO,이한구,SONG, IN BEOM,송인범,SEO, JUNG KI,서중기,NAM, TACK IL,남택일,SHIN, SEUL BUM,신슬범,PARK, YEONG TEAK,박영택
申请号：
KR1020100085907
公开号：
KR1020120022368A
申请日:
2010.09.02
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A transdermal preparation containing S-citalopram is provided to reduce side effect and to improve drug compliance.CONSTITUTION: A transdermal preparation contains 5-70 wt% of S-citalopram as an active ingredient. The transdermal preparation comprises: a support(1) a drug layer(containing S-citalopram, skin permeation enhancer, and adhesive, 2) and S-citalopram formed of release film(3). The skin permeation enhancer of the drug layer is diethylene glycol monoethyl ether, isopropylmyristate, isostearyl glyceryl ether, propylene glycol, propylene glycol monolaurate, propylene glycol monocarprylate, polysorbate 80, sorbitan sesquioleate, caprylocaproyl macrogolglyceride, or oleyl macrogolglyceride.COPYRIGHT KIPO 2012본 발명은 항우울제인 에스-시탈로프람을 유효성분으로 한 경피흡수제형에 관한 것으로서, 피부 투과 누적양이 높고, 약물을 일정하게 방출하는 에스-시탈로프람 경피흡수제를 제공한다.
