INSTYTUT IMMUNOLOGII I TERAPII DOŚWIADCZALNEJ POLSKIEJ AKADEMII NAUK
发明人:
LIPIŃSKI TOMASZ,GAMIAN ANDRZEJ,ZUZIAK EWA,KORZENIOWSKA-KOWAL AGNIESZKA,GÓRSKI ANDRZEJ
申请号：
PL08712679
公开号：
PL2117568T3
申请日:
2008.02.08
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
A method of preparation of purified bacteriophage with increased antibacterial activity, in which from bacterial lysate of phages is obtained, advantageously in the presence of lysozyme, chelating factor and detergent, in a continuous manner with ultrafiltration on membranes, the phage containing high molecular mass preparation, devoid of bacterial cell wall and other contaminants, free of toxins and endotoxins, active in tests of bacterial lysis, which is characterized by chromatography HPLC, In SDS-PAGE electrophoresis, immunoblotting, biological tests of bacterial lysis, and is dedicated for phage therapy of bacterial infections and tumors and for production of phage deriving pharmaceutical preparations.
