INSTYTUT IMMUNOLOGII I TERAPII DO&SACUTE；WIADCZALNEJ PAN;INSTYTUT IMMUNOLOGII I TERAPII DO&SACUTEWIADCZALNEJ PAN
发明人:
LIPI&NACUTE,SKI TOMASZ,GAMIAN ANDRZEJ,ZUZIAK EWA,KORZENIOWSKA-KOWAL AGNIESZKA,GORSKI ANDRZEJ,LIPI&NACUTESKI TOMASZ,LIPI&NacuteSKI TOMASZ,GÓRSKI ANDRZEJ
申请号：
PL38173007
公开号：
PL212099B1
申请日:
2007.02.09
申请国别(地区):
PL
年份:
2012
代理人:
摘要：
A method of preparation of purified bacteriophage with increased antibacterial activity, in which from bacterial lysate of phages is obtained, advantageously in the presence of lysozyme, chelating factor and detergent, in a continuous manner with ultrafiltration on membranes, the phage containing high molecular mass preparation, devoid of bacterial cell wall and other contaminants, free of toxins and endotoxins, active in tests of bacterial lysis, which is characterized by chromatography HPLC, In SDS-PAGE electrophoresis, immunoblotting, biological tests of bacterial lysis, and is dedicated for phage therapy of bacterial infections and tumors and for production of phage deriving pharmaceutical preparations.
